Effect of Sesame Oil on the Inhibition of Experimental
Autoimmune Encephalomyelitis in C57BL/6 Mice
Pakistan Journal of Biological Sciences
G. Mosayebi , A. Ghazavi , H. Salehi , M.A. Payani and M.R. Khazaei
Abstract:
Sesame oil was evaluated in the treatment of in C57BL/6 mice.
It has profound anti-inflammatory activity and been traditionally
used to treat inflammatory disorders.
EAE was induced by immunization of 6-8 week old mice with
MOG35-55 with complete Freunds adjuvant.
Therapy with sesame oil was started on day 3 before the
immunization.
Total Antioxidant Capacity (TAC) was assessed by Ferric
Reducing-antioxidant Power (FRAP) method.
Nitric Oxide (NO) production was also estimated by Griess
reaction.
For histological analysis, mice brain was harvested and sections
were stained with Hematoxylin-Eosin.
After daily intraperitoneal dosage the sesame oil significantly
reduced the clinical symptoms in C57BL/6 mice with EAE.
Also, treated mice displayed a significantly delayed disease
onset compared with control mice.
Sesame oil significantly increased TAC, but it=s effect on serum
nitrite production was not significant.
Typical brain leukocyte infiltration was observed in control mice
compared with treated mice.
Present results suggest for the first time that sesame oil therapy
may be effective in the prevention of symptomatic EAE.
This resistance to encephalomyelitis may be associated with
inhibition of oxidative stress.
Pakistan Journal of Biological Sciences
Year: 2007 | Volume: 10 | Issue: 11 | Page No.: 1790-1796
DOI: 10.3923/pjbs.2007.1790.1796
-----------------

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

Spamming Dickwadd

On Jun 6, 7:33 am, Rustty the Other Spamming Dickhead
 wrote:On Jun 5, 8:56 pm, ironjustice
 wrote:snip <<

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-------------------

Effect of Sesame Oil on the Inhibition of Experimental
Autoimmune Encephalomyelitis in C57BL/6 Mice
Pakistan Journal of Biological Sciences
G. Mosayebi , A. Ghazavi , H. Salehi , M.A. Payani and M.R. Khazaei
Abstract:
Sesame oil was evaluated in the treatment of in C57BL/6 mice.
It has profound anti-inflammatory activity and been traditionally
used to treat inflammatory disorders.
EAE was induced by immunization of 6-8 week old mice with
MOG35-55 with complete Freunds adjuvant.
Therapy with sesame oil was started on day 3 before the
immunization.
Total Antioxidant Capacity (TAC) was assessed by Ferric
Reducing-antioxidant Power (FRAP) method.
Nitric Oxide (NO) production was also estimated by Griess
reaction.
For histological analysis, mice brain was harvested and sections
were stained with Hematoxylin-Eosin.
After daily intraperitoneal dosage the sesame oil significantly
reduced the clinical symptoms in C57BL/6 mice with EAE.
Also, treated mice displayed a significantly delayed disease
onset compared with control mice.
Sesame oil significantly increased TAC, but it=s effect on serum
nitrite production was not significant.
Typical brain leukocyte infiltration was observed in control mice
compared with treated mice.
Present results suggest for the first time that sesame oil therapy
may be effective in the prevention of symptomatic EAE.
This resistance to encephalomyelitis may be associated with
inhibition of oxidative stress.
Pakistan Journal of Biological Sciences
Year: 2007 | Volume: 10 | Issue: 11 | Page No.: 1790-1796
DOI: 10.3923/pjbs.2007.1790.1796
-----------------

Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh


Man Is A Herbivore!
http://tinyurl.com/4rq595


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk